Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)-
Lycorine hydrochloride
CAS: 2188-68-3
Molecular Formula: C16H17NO4
Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)- - Names and Identifiers
| Name | Lycorine hydrochloride |
| Synonyms | LYCORIN LYCORINE Lycorine HCl (-)-LYCORINE NARCISSIN(P) Hydrochloric Lycorine Licorin hydrochloride Lycorine hydrochloride Galanthidine hydrochloride Lycoran-1-alpha,2-beta-diol, 3,3-alpha-didehydro-, hydrochloride Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)- |
| CAS | 2188-68-3 |
| InChI | InChI=1/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1 |
Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)- - Physico-chemical Properties
| Molecular Formula | C16H17NO4 |
| Molar Mass | 287.31 |
| Melting Point | 206 °C |
| Boling Point | 477.4°C at 760 mmHg |
| Specific Rotation(α) | +43° |
| Flash Point | 242.5°C |
| Solubility | DMSO : 25 mg/mL (77.22 mM; Need ultrasonic) |
| Vapor Presure | 6.37E-10mmHg at 25°C |
| Appearance | White powder |
| Color | White to off-white |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 1 month. |
| Sensitive | Sensitive to light |
| MDL | MFCD00243111 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Lycoris radiata bulbs. |
Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)- - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)- - Reference
| Reference Show more | 1. Niu Wei and Pan Dongming. Study on Extraction Methods of Narcissus Alkaloids from China [J]. Anhui Agricultural Sciences 2012(19):10018-10019. 2. Peng Cong, Xu Jia, Wu Chunlian. Effects of Lycorine Hydrochloride on Eca-109 Proliferation and Apoptosis of Human Esophageal Cancer Cells [J]. Journal of Xihua Normal University (Natural Science Edition), 2015(36):7-11. 3. [IF = 2.044] Xu Chen et al."Ionic-Liquid-Based Infrared-Assisted Extraction (IL-IRAE) Coupled with HPLC-MS: a Green and Convenient Tool for Determination of TCMs." Chromatographia. 2017 Feb;80(2):335-340 |
Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)- - Nature
Open Data Verified Data
crystals of colorless prisms. Melting point 275~280 °c (decomposition). Insoluble in water, slightly soluble in ethanol, the stems and branches of ephedrine cut into 2 ~ 4cm long, plus chloroform and petroleum ether, soluble in acidic aqueous solution. Its commercial form is usually its hydrochloride, the crystals of which are long needle-like crystals with a melting point of 217 ° C. (decomposition).
Last Update：2024-01-02 23:10:35
Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)- - Preparation Method
Open Data Verified Data
It is usually extracted from Lycoris radiata. Take Lycoris sativa L. Bulb powder, extract with ethanol reflux for 6h, cool, filter, extract repeatedly for 3 times, combine the filtrate, concentrate to dryness; Dissolve the concentrate with 2% hydrochloric acid, filter, the filtrate was washed with chloroform; The acid water washed with chloroform was basified with Na2 C03, and then chloroform was added to precipitate lycorine solid in the middle of the chloroform alkaline water layer. After filtration, it was dissolved and concentrated with 2% HC1, crystal available lycorine hydrochloride. Pseudoephedrine.
Last Update：2022-01-01 11:15:16
Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)- - Use
Open Data Verified Data
small doses have expectorant effect, large doses of oxalic acid to add 8~10 times the water and vomiting effect, but also have spasmolytic effect.
Last Update：2022-01-01 11:15:16
Supplier List
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Product Name: Lycorine chloride Visit Supplier Webpage Request for quotationCAS: 2188-68-3
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Multiple SpecificationsSpot supply
Product Name: Lycorine chloride Visit Supplier Webpage Request for quotationCAS: 2188-68-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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